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Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
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muscle soreness
Apr 18, 2007

When I work out with weights it takes me 2 days to no longer feel extremly sore and stiff. Is this extra soreness i feel due to miticrondal changes from my meds? I am on Sustevia,Ziagen,Retonivir,Reyataz. I also take crestor and pheno pibrate. my cd4 is 1000. my VL is < 50 ml/ I need to work off some of the unexplained weight gain I now have since starting reyatez about 8 months ago...I have put on 20 pounds, mostly around my gut. Not sure why, but how can I decrease all this muscle soreness??


Response from Dr. Henry

There is not much evidence that your current regimen would have much of a negative impact on mitochondrial function but there could be potentially patients who are more genetically susceptible that generally reported. Many HIV- persons get lots of muscle soreness after exercise so it can be tough to sort out the added contribution of either HIV infection or any one of a combination of antiretroviral medications. I would discuss with your HIV specialist to see if there is any evidence of muscle damage (Crestor and/or a fibrate could contribute to muscle problems). If nothing there consider consultation with a physiotherapist or exercise trainer to discuss your goals and experience to see what they may offer as suggestions to help you burn calories while addressing your soreness and stiffness. KH

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