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PEP+false positive?
Feb 7, 2007

Gentlemen,

I guess this is a side-effect of PEP question: How big is the chance, after succesfully completing a PEP course (although started app. 70 hrs after potential exposure with an unknown status woman), that an HIV test will come out as a false positive? I read that there is a chance that anti-bodies will be detected but that infection had been aborted due to PEP, so no infection actually took place.

Furthermore, is there a specific test, different from the standard test, that needs to be used?

Best regards

Response from Dr. Henry

Use of antiretroviral therapy for PEP per se does not generally cause a positive HIV antibody test. Checking directly for HIV RNA is one means to sort out whether HIV infection occurred but was partially aborted by use of PEP as is follow-up antibody testing after 3-6 months.



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