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Kidney dysfunction
Feb 2, 2007

I've been experiencing kidney dysfunction (very frequent urination, slighty abnormal blood tests) which my Dr. attributed to the Viread I was taking. I switched to Abacavir. I was reading that Acabvir is not recommended for patients with kidney disorder. Is that only because of fear of HSR? I tested negative for the genetic varient that is somewhat predictive of potential HSR. Do you think it's a bad idea for me to be taking Abacavir? (I am, and have been, also taking Sustiva.) Much thanks.

Response from Dr. Henry

Abacavir generally has less of a potential impact on kidney function than tenofovir. Switching to abacavir from tenofovir in patients with pre-existing or developing renal dysfunction often is a reasonable recommendation (I have numerous patients with some degree of renal dysfunction taking abacavir who appear to be tolerating the abacavir without further aggravation of their renal problem). KH

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