Restart Meds after Lactic Acidosis
Jan 19, 2007
I spent nearly 20 years on mostly NNRTIs and my T-cell counts were well maintained. I started a lactic acidosis event. I stopped all meds ( most recently just Combivir). I have regained most of my strength, but my viral load and T-cell count deemed that after 8 months of no retrovirals I needed to start a new regime. My Dr. has added NNRTIs to this regime, is this wise? What are the alternatives to using this class of drugs?
Response from Dr. Henry
Lactic acidosis is most often seen in regimens containing the thymidine nucleoside reverse transcriptase inhibitors (NRTIs not NNRTIs) particularly D4T > AZT. After lactic acidosis oftren NRTIs can be used as a part of an effective regimen but the D4T or AZT is usually replaced by abacavir or tenofovir. I have also avoided NRTIs altogether in some patients using a double boosted PI regimen with reasonable effectiveness. KH
Get Email Notifications When This Forum Updates or Subscribe With RSS
- What Do Genital Warts Look Like In Early Stages?
- What Are The Stages Of Chlamydia?
- What Are The Odds Of Contracting Genital Herpes After Sleeping With Someone Who Has It But Not An Outbreak?
- What Are The Causes Of Recurring Shingles?
- Time It Takes To Get Genital Warts After Exposure
- Is Tea Tree Oil Used For Warts With Hpv?
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.