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Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
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what new meds are coming out?
Dec 22, 2006

Are there any new meds coming out soon with much less side effects? What we can expect from future treatments?

Response from Dr. Henry

The major new meds in the pipeline for the next year involve 2 new classes; 1) HIV integrase inhibitor (Merck drug likely to be approved in 2007-side effect profile looks good though large long-term experience is lacking as is true for any new drug); and 2) CCR5 inhibitors (Pfizer drug likely to be approved next year-it too seems to have a reasonable side effect profile). Future treatments are likely to involve mostly once or twice a day dosing with reasonable side effect profiles and often activity against strains of HIV resistant to many of the current medications. There are new drugs being developed in older classes and some other new classes being developed but those are the two nearest approval in the US. KH

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