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Dec 1, 2006

Hello what treatment of hepatitis C (genotype 1) by (protease inhibitors) exist on the market? Are they all provided in hospitals? What is the cost of the treatment.

Thank you very much

Response from Dr. Conway

There is a tremendous research effort underway to develop alteratives to combination therapy with interferon and ribavirin for HCV infection. This is especially true for genotype 1 infection, where the response rates are a bit lower. To date, the compounds are effective, yet toxic. The most promising ones are from Idenix and Vertex (the latter company producing VX-950), with the Vertex compound being in more advanced stages of clinical trials and showing more promising results. To get access to these medications, however, you need to be enrolled in a clinical trial. This being said,if all goes well, the medications may become available more broadly within 3-4 years.



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