Advertisement
The Body: The Complete HIV/AIDS Resource
Follow Us Follow Us on Facebook Follow Us on Twitter Download Our App
Professionals >> Visit The Body PROThe Body en Espanol
Read Now: TheBodyPRO.com Covers AIDS 2014
   
Ask the Experts About

Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
           
Rollover images to visit our other forums!
Recent AnswersAsk a Question
  
  • Email Email
  • Glossary Glossary


Old HIV
Nov 6, 2006

What benefits, if any, do you expect from treating "old HIV". I'm assuming people who've gotten infected recently have newer mutations with various resistances, etc. I'm a long-term-non-progressor, and probably was infected about 25 years ago. I have not been in any situations which would have re-exposed me to additional HIV. As my CD4s are slowly but surely bottoming out, whenever I start meds, do I have any higher likelihood of response and success? Would you approach what you prescribe any differently for me, perhaps fewer drugs than "today's infectees"? Or does the age of my HIV not really matter? (My VL has never been higher than 54 and has been undetectable since '99).

Also, if someone's CD4 goes <200 but has relatively-high percentages, would their treatment be approached any differently than someone who was, say, 140/13%? (And let's assume no VL in each case).

Response from Dr. Conway

Someone who is a long-term non-progessor has defined him or herself as someone whose immune system is able to keep the virus under control quite efficiently without the use of antiviral drugs. This being said, at some point this control may be lost and I would use the same criterion I use to recommend the initiation of treatment as I use in more recently infected individuals. If the CD4 count approaches 350 or if it is decreasing quite rapidly, I recommend treatment. I would always go with a once a day regimen, and I really like the single Atripla pill (containing 3 drugs), as long as the Sustiva component of it is not a problem for the person.

To address your two other questions, if the CD4 count is below 200 and the percentage is still high (say 16% or more) I would still start treatment unless there is a severe acute illness that could have decreased the CD4 count artificially. I would then make sure it goes up after the illness passes.

As for a different regimen in more recently infected individuals, I do not do this as our primary resistance rates are quite low. To be safe, however, if primary resistance is a concern, we may recommend that a resistance test be done before the treatment is selected.



Previous
hiv meds and avascular necrosis
Next
Do people with HIV also get cancer?

  
  • Email Email
  • Glossary Glossary

 Get Email Notifications When This Forum Updates or Subscribe With RSS


 
Advertisement



Q&A TERMS OF USE

This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.

Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.

Review our complete terms of use and copyright notice.

Powered by ExpertViewpoint

Advertisement