Nov 1, 2006
Thank you Dr Henry for the response.I realy appreciate.
You talked of rehablitation-how since i've done some physio-therapy with minimal response?and you have also talked of variable course-which one is the best variable course for toxoplasmosis.I live in a country where most of the vital drugs are not found easily.Doctors here have said the lesions are located on the right side of the brain.Please advise on where i can source the right medications.
Response from Dr. Henry
Treatment of toxoplasmosis often is with pyrimethamine + sulfadiazine (with leukovorin). Clindaymycin, azithromycin, clarithromicin can be substituted for the sulfadiazine in some patients. TMP-SMX can also be used to treat CNS toxoplasmosis in certain patients. Besides anti-toxoplasmosis drugs, optimal antiretroviral therapy to hopefully increase CD4 recovery can prevent development of new CNS toxoplasmosis lesions and aid recovery. There is no drug that specifically helps the brain to repair itself. That is a highly variable process which is often frustrating and can sometimes wind up with some level of ongoing deficit despite adequate treatment of both HIV and toxoplasmosis. KH
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