|Type 2 diabeties
Sep 13, 2006
Several of my friends included one guy who has been HIV for 25 years have suddenly been diagnoised with type 2 diabeties, is this somehow related to the HIV medications, my doctor doesn't want to admit this?
| Response from Dr. Henry
Good question. The incidence of diabetes is increasing in the general population so it can be difficult to sort out the contribution of HIV or anti-HIV medications. The increasing rates of obesity in the US contributes to the overall increase in the general population. Risk for diabetes increases with age and also can have a genetic component so that persons with close relatives with diabetes are at increased risk. Effective HIV treatment can reverse weight loss due to HIV/AIDS but could then contribute to risk for diabetes as a patients survives their HIV for a long time. Certain HIV medications may trigger more metabolic/lipid/glucose abnormalities than other medications with some of the susceptibility to HIV drug effect perhaps being genetic ( a small % of patients may be highly susceptible when many/most are not). HIV specialists can usually sort out if a given regimen is significantly contributing to new onset diabetes and what switch options are available. KH
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