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Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
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Extremely tired and loosing weight
Jul 21, 2006

My boyfriend has been on AZT for ten years and about six months ago he started getting sick. We had tests done and our doctor decided that the AZT was no longer working. He was put on Sustiva and Kivexa, but could not support the Sustiva, so that was changed to Norvir and Reyataz. Now his CD4 is back to 460 and the hiv level is undetectable. Evrything should be well, but it is not. He has 12000 platelets, and despite several medication treatements, they have not gone up. Apparantly this is a side effect of the long term AZT use. Now his eyes are very yellow, and he is loosing a lot of weight. He is extremely tired and just wants to sleep all day. Until six months ago, he was extremely active. He has just had a negative test for toxoplasmosis., and we cannot seem to find out what is wrong with him. Is there any other solution for the lack of platelets and are the other syptoms related. Our doctor does not seem to have a solution, and he is getting sicker every day.

Response from Dr. Henry

Reyataz can cause jaundice so his liver function needs to be assessed. Low thyroid and testosterone levels, anemia, sleep abnormalities, depression, undiagnosed infections and many other conditions can contribute to fatigue so a full history and physical evaluation is often required to come up with some possible explanations and treatment options. KH

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