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are protease inhibitors the cause of lypoatrophy or is hiv
Jun 9, 2006

the same as title. is lypoatrophy a side effect of using protease inhibitors or is lypoatrophy a direct cause, oi, of being hiv positive. i am trying to determine whether the treatment providers have some responsibility for the costs of treating cosmetically the facial side effects.

Response from Dr. Henry

Fat loss (lipoatrophy) probably is multi-factorial so the answer is both. Aging, longer time with HIV, a lower CD4 count--those factors have been linked to fat loss. Certain HIV drugs (most notably D4T and AZT) have been linked to fat loss. Protease inhibitors may be linked but the connection is less clear and may vary by drug and genetic background of the patient. KH



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