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HIV and Hemochromatosis
Jan 24, 2006

Dear Sir,

HIV-1 NEF down-regulates the hemochromatosis protein HFE, manipulating iron homeostasis. PNAS 2005:102:11017-22

HFE mutation in hemochromatosis changes the interaction between HIV and macrophages!

Sincerely Yours Friedrich Flachsbart

Response from Dr. Henry

Your feedback with those references is appreciated. The clinical implications of that laboratory finding is unclear and needs more study.



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