|Do I really need norvir?
Jul 6, 2005
Hello, I am currently on Reyataz and Truvada. I am doing very well virologically (month 2 I became undetectable) on it. However, I recently saw a different HIV specialist to get another opinion on something my regular doctor had said. This guy says that I need Norvir to boost the Reyataz and that without it, the combination is all wrong. My doctor says that I am doing well so he doesn't see the need to add anything. So who should I listen to? Is the Norvir really as crucial to the combination as the other guy thinks or is my medicine find since I am doing well on it?
| Response from Dr. Conway
There is clearly an interaction between Reyataz and the Viread part of Truvada that reduces Reyataz levels such that they could easily be sub-therapeutic. The Norvir restores the Reyataz to therapeutic levels. To date, you have "gottten away with it", but the benefit of the regimen may not be long-lasting without the Norvir. And it is only 100 mg Norvir/day. Think of it as a convenient one pill per day insurance policy...
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