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Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
           
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Where are the Medicines with Less Side Effects?
Jun 22, 2005

We keep hearing about new HIV medicines with less side effects, but what are they?

Viread? Fine for some, but terrible for others, just like all the other drugs.

Reyataz? Lexiva?

All the approved HIV drugs are antivirals, which work by attacking processes that happen in the healthy cell as well as the virus.

This can never lead to a cure.

Why aren't HIV clinicians crying out for increased research into topics such as methods for decreasing the cell-death of healthy CD4s and immune-based therapies to reduce the autoimmune responses to HIV infection?

Response from Dr. Henry

Treatments based on immune-related therapy are under study but have been slow in developing due partly to the fact that we know relatively less about the human immune system than we do about HIV. From a commercial standpoint companies are not as motivated to produce drugs which are "out of the box" or work by different mechanisms. Your points are well-taken. KH



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