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From 3TC , What Next?
Jun 8, 2005

I have been on AZT, 3TC and Crixivan since 1997. In March this year I did a resitance test at Mirriam Hospital in Providence, Rhode Island that shows some resistance associated with 3TC. My health has been on a downward trend for most of last year and this year. Is there a combination that I can switch to that would replace 3TC?

Winstone Zulu Kabwe, Zambia

Response from Dr. Henry

3TC resistance is fairly common. If that is the only resistance that shows up based on lab tests and history of treatment then you likely have many options (other than 3TC or FTC). Often switching to a boosted protease inhibitor and switching your NRTI from 3TC to an alternative can results in full suppression/control of viral replicaiton. KH

Steven Johnson Syndrome after effect, tearing eyes.

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