May 8, 2005
Meds virgin in the UK but Doc has suggested Combivir/Tenofovir/Efavirenz what do you think of this combination and hasn't Conbivir been associated with Lipodystrophy?
| Response from Dr. Conway
Of all the combinations we have evaluated in clinical trials, lamivudine, tenofovir and efavirenz is associated with the lowest incidence of lipodystrophy over 3-5 years. Combinations including zidovudine do not have as much of a positive track record, but are not as bad as those including stavudine with respect to lipodystrophy. Many prescribers would feel comfortable giving you 3 medications rather than 4 and you should discuss with your doc why he/she feels you should be on zidovudine along with lamivudine, tenofovir and efavirenz.
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