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Meds Virgin
May 8, 2005

Meds virgin in the UK but Doc has suggested Combivir/Tenofovir/Efavirenz what do you think of this combination and hasn't Conbivir been associated with Lipodystrophy?

Response from Dr. Conway

Of all the combinations we have evaluated in clinical trials, lamivudine, tenofovir and efavirenz is associated with the lowest incidence of lipodystrophy over 3-5 years. Combinations including zidovudine do not have as much of a positive track record, but are not as bad as those including stavudine with respect to lipodystrophy. Many prescribers would feel comfortable giving you 3 medications rather than 4 and you should discuss with your doc why he/she feels you should be on zidovudine along with lamivudine, tenofovir and efavirenz.



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