|Follow Up: Bdna
Apr 6, 2005
Dear Dr Conway,
This is my follow up my story , please see the link below to refresh your memory,
Unfortunately I have been unable to get the test for direct sequencing done but am still experiencing clinical symptoms and weight/muscle loss with twitching. I have repeated BDNA tests done with many so called false positives ranging from 1000 up to 12500 and then down back to undetectable within a space of a few days. I need some answers and a proper diagnosis. During all this, my Elisa and WB have all been and still are negative. Please advise me what to do, I am willing to travel to any country in the world to get a proper diagnosis as I feel South Africa does not have the necessary medical expertise needed for my case. If you need, I will fax or email you a copy of my results showing multiple positive BDNA tests but still elise/bdna negative.
I appreciate your replies, they seem to be the only sensible ones that I have come across.
Thanks and regards,
| Response from Dr. Conway
I am sorry to hear of your ongoing situation, and would hope that some additonal testing be available to you. The key here is to be able to confirm by some other means than the bDNA test that you are, indeed, infected with HIV. I am at a bit of a loss to explain the ongoing negative antibody test. I would have a number of theories (including the posssibility that you are not, in fact, infected with HIV), but these would be theories not really based on any facts in your case.
I might propose that, if the sample that had over 10,,000 HIV copies/mL on the bDNA test is still available, it be sent for resistance testing. Even if there are no resistance mutations, if it generates a sequence of HIV, it will confirm that you are carrying the virus. If not, it would be one more piece of evidence that you may not, in fact, be infected.
Once again, good luck with this ongoing situation.
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