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Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
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Discolored lips
Mar 25, 2005

I am having a problem that I don't hear too much about, my lips are turning darker and darker. The flesh inside my mouth is bright red. I also have severe dry mouth most of the time. I have been HIV+ for about 10 years, am on Sustiva, Zerit, and Videx EC, Marinol, Testim, and Oxandrin. I've had ITP (and had a splenectomy), and also have cirrhosis and lipodystrophy, and have really bad rashes around both of my ankles. My numbers seem ok - undetectable and 600 tcells. I have a hard time gaining weight, I weigh 117 lbs. even though I eat all the time. Please let me have your opinion about this, as it is highly embarrassing. Have you ever heard of lips that are discolored (darkening)?



Response from Dr. Henry

I assume that your oxygen levels are OK and that your lungs and heart are functioning. Hormone abnormalities and iron overload syndromes can cause some darkening like you describe so a general evaluation and perhaps a visit to a dermatologist might help pin down what is going on. KH

URGENT: Should I stop med now?
Joint pain/Urination problems/Rising VL

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