Oct 28, 2004
I have recently come across research studies on interrupted medication regimes ie two weeks on and two weeks off, or five days on and two days off, which suggest that there is no detrimental effect on viral load or CD4. I am quite excited with these findings as there are enormous benefits in terms of cost savings and convenience. My doctor is not so excited as he is concerned that any relaxation of the rigid daily regime will undermine overall adherence. What do you think?
Response from Dr. Henry
Two weeks on and two weeks off is not recommended though the strength of the recommendation depends on which drugs a person is taking and what the treatment history is. There is a high level of concern about increasing resistance rates. The weekend off (5 on 2 off) approach has been looked at in a very small study and is nowhere near ready for prime time. Treatment interrruption studies have failed more often then not so the concept has to be considered experimental and risky at the present time. There are numerous studies underway that may clarify the risks and benefits over the next several years but for most patients it is wise to continue treatment. KH
Get Email Notifications When This Forum Updates or Subscribe With RSS
- Dizziness After Oral Sex Worried I Have HIV
- Itchy Red Spots After Sex With Stripper Sign Of HIV AIDS
- Loose Stool After Insertive Anal Sex With Condom What Are The Chances Of HIV
- Penis Discharge After Rubbing Vagina Worried I Have HIV
- White Tongue After Unprotected Oral Sex Without Ejaculation Worried I Have HIV
- Can Mucous In Stool Be An Std?
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.