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Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
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Muscle Atrophy
Oct 20, 2004

I have had severe peripheral neuropathies for 8 years now, which has resulted in severe atrophy in the calf muscle of my right leg. I have tried physical therapy and supplements (Juven) and nothing seems to work. Is there a plastic surgery procedure you can recommend or any other alternative? Thank you.

Long-term Fighter in NY

Response from Dr. Henry

For increasing muscle mass an optimum mix of good diet (Protein supplements), targeted exercise, and hormone background (testosterone or other anabolic steroids) usually provides some help. Trying to stop any drugs that could aggravate the neuropathy can help sometimes though in long term cases like yours I often observe less benefit. I get help from neurologists and physiatrists when I run into tough cases like you describe. It is unclear whether any effort to target/reverse mitochondrial toxicity helps in some cases. KH

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