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Resistant to 3TC
Aug 25, 2004

I am on 3tc, efavirenz and ddi. My doctor took a resistance test and said I have M184V the mutation for 3tc. Can I just change the 3tc to tenofovir or do I have to change another drug too? I was on therapy for 2 years and my viral load just began to shoot up.

Response from Dr. Henry

I would consider adding another drug and perhaps a major over-haul of your regimen depending on the degree of viral load rebound, CD4 counts, treatment history, etc. KH



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