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Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
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Neuropathy from Fosamax?
Jul 28, 2004

I have been on a combination of VidexEC, Viread, and Kaletra (though I've been on some combination of a protease inhibitor and other drugs since 1996).

Recently I was diagnosed as having osteopenia. My doctor started me on once-a-week Fosamax. After about 2 weeks, I started getting the feeling of having a low-grade fever constantly, then severe and extremely painful neuropathy in my lower legs, and finally a body rash. After 4 weeks on Fosamax, I stopped. The neuropathy continued to get worse. My doctor prescribed 800 mg Motrin for the pain, which works for the most part.

It has been over a month since I stopped taking Fosamax, but the pain is still there.

Have you ever heard of this before in an HIV patient? And do you think the pain will eventually stop, or do you think permanent damage has been done?

Any suggestions on what to do?


Response from Dr. Conway

The main side effects of Fosamax are gastrointestinal in nature. Although muscle and joint pain are reported in a few percent of patients, neuropathy would be distinctly unusual. Even rash is not well reported. I would look elsewhere for the cause of your symptoms.

Can't tolerate drugs
Parkinson's diagnoses from 20 years + of ART

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