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Possible Long term consequences for short term use of HIV drugs?

Jul 26, 2004

(Follow up question) Are there any long term or permanant damage from taking HIV meds for one week.

Permanant DNA damage? Should I not have kids?

Permanent bone marrow damage? Are my bones likley ok?

Anything else? Thanks


Response from Dr. Conway

Anti-HIV drugs interfere with DNA synthesis, so there is always the theoretical risk of cancers developing many years later in patients who are on long-term therapy. Also, there are some acute side effects that can develop while on shorter term therapy, some of which can be quite severe.

Although we will not know for sure for 20 more years, it seems to me that the risk of any permanent damage from one week of antiretroviral therapy is extremely unlikely if there were no acute symptoms while on therapy.

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