Viral loads in other body fluids
Jul 25, 2004
Your discussion of very, very rare cases of infected folks repeatedly testing negative is most interesting.
My question is this: is it true that HIV levels are usually higher in sperm than in blood? If so, have some of those rare cases been diagnosed by doing a DNA PCR and/or ELISA on sperm and/or cells in the mouth...establishing infection that way when PCR's and ELISA's on cells/blood have been negative despite a clinical picture that suggests HIV?
Response from Dr. Conway
Numerically, the amount of HIV that is present may vary from one reservoir to the other. It will tend to be the highest in the plasma or in the circulating cells that turn over the most rapidly (usually CD4 positive lymphocytes).
There are rare cases where the most virus was isolated from the brain, the virus presumably replicating in an area where it was beyond the control of the immune system.
As far as semen in concerned, the virus is either in the seminal fluid or in the inflammatory cells that are contained in the ejaculate. Generally, the more cells there are (as in the case of a person who has another STD, such as gonorrhea or chlamydia), the more virus there will be. It may also be that the seminal fluid represents a protected reservoir that can accumulate virus more than in the blood. However, I am not aware of any cases where an individual was only diagnosed by the presence of virus in the seminal fluid or sperm, and had no virus present anywhere else, and ahd not detectable anti-HIV antibodies in the blood.
Get Email Notifications When This Forum Updates or Subscribe With RSS
- Blowjob From A Prostitute And AIDS
- Fatigue After Anal Sex Top Sign Of HIV AIDS
- Itchy Vagina After Anal Fingering Sign Of HIV AIDS
- Muscle Ache After Sex With Hooker Sign Of HIV AIDS
- Sore On Penis After Oral Sex Hooker What Are The Chances Of HIV
- Vomiting After Swallowing Cum Worried I Have HIV
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.