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Needle stick injury
Jun 4, 2004

My son is an intern medical doctor who has had a needle stick injury from a very sick HIV infant.He has been supplied by his hospital with Zidovudine(100mg)twice a day and been advised to take Indinavir(400mg)every 8 hours as well because concentrations of the virus are increased in an infant.Is this combination adequate, effective and can he expect severe side effects for the duration of his 28 day treatment against being infected with HIV.As a mom, I don't have much medical knowledge but am concerned about his chances of contracting HIV from a needle stick injury(side of his hand, but was wearing gloves)of this nature and also side effects of the medication.

Response from Dr. Henry

Iwasnt sure where your son is working and which medications are available. ZIdovudine and Crixivan as the 2 drugs would be somewhat usual. I usually would recommend adding 3TC to that. If in the US or other western countries use of tenofovir is also an option as are Sustiva or other PIs besides Crixivan. GI side effects are very common during the 4 weeks prophylaxis is usually given. KH



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