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Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
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neuropathy in feet
May 20, 2004

neuropathy in feet ive recently had worse pain in feet (no d meds) & tried amiltryptiline, neurontin without success, now on morphine & effexor (my psy says that effexor also works for physical pain; do u know something about this? thks ps:everyone can respond on

Response from Dr. Henry

3TC can also aggravate neuropathy in some patients. There are several clinical trials looking at new drugs for neuropathy. One is using a potent form of capsaicin that is painted on the involved area. The ACTG is also about to open a study using a new drug that looks promising for neuropathy (don't have that reference handy but if there is an ACTG site near you in the US I would contact them). I have had a few patients get some further relief with effexor. Some patients get some benefit from acupuncture or some alternative meds (such as L-carnitine, NAC, some vitamins--see Jon Kaiser's book Healing HIV or the web site for some details). I have not had any one approach work consistently. I also get a pain clinic to help me out in some cases. KH

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