May 10, 2004
I have severe candida in my esophagus which does not respond to any treatment. Is this common among patients with low T-cell count and what are some possible solutions.
Response from Dr. Conway
The main thing for Candida that does not respond to treatment is to boost your immune system with HAART. This way, your body's own defenses can complement the effect of the antifungal drugs.
In the meantime, there are some newer oral antifungal agents (such as itraconazole) that sometimes work when other approaches fail. Older intravenous drugs such as amphotericin B can be used for a short time to address a serious problem for a number of days. However, when it is used for too long, the amphotericin B can be toxic to the kidneys, so it is best used "strategically".
The best bet is to get your body to pitch in the fight...boost your immune system with HAART.
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