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Does Immuno Reconstruction syndrome exist?
Feb 4, 2004

I have a friend who is in advanced state of AIDS with sarcoma on the legs. His doctors are changing his treatment and have spoken of "immuno reconstruction syndrome" - saying that as a reaction to new drugs, he will get sickers before he gets better. Is there such a syndrome?

Response from Dr. Henry

Yes-in a minority of patients the immune reconstitution phenomenon is observed where a dormant/damaged immune system comes to life and begins reacting against existing germs (such as some viruses or bacteria) that may pardoxically cause some symptoms to flare up for a while. KH

travel to brasil -- yellow fever
Starting treatment after years of non-treatment

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