Re: skin pain
Nov 14, 2003
First of all, thank you so much for answering my previous question and for the great help you give to all of us. Yes, you were right, my brother did have herpes zoster in that area and on the left as well. That was a long time ago when he was on monotherapy before he started HAART in 1996. Last year he had the same pain that lasted about 10 days. So you think it is the herpes zoster? He doesn't need to change the 3TC? But does this mean also that he is not controlling the HIV virus well enough? Wish you all the best
Response from Dr. Conway
Thanks for your kind comments about the site.
The role of HAART is to control viral replication to prevent any further damage to the immune system. In some cases, the immune system has become so weak that it takes a long time to build itself back up. The fact that ongoing clinical events occur (such as recurrent shingles) is often not a matter that the medications are not working, but more a matter that the immune system is still weak. This can get better with time, but in some cases it does not. There are many studies being done to boost the immune system in people who are responding to HAART. This may involve the use of things like IL-2, and perhaps some newer things that may have less side effects. Hopefully, one (or more) of these approaches will make it out of clinical trials and into clinical practice.
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