|Side effects not getting better
Oct 31, 2003
I have been on Sustiva, Epivir, and Videx EC for the past month. I didnt get any rash or dreams, but during the day I feel as if I am drunk. I also have crying spells, difficulty concentrating, fatigue and dizziness. I thought after a month this would pass but it hasn't. They want to switch the Sustiva to Viramune. Will this help any of my symptoms? I am in my last semester in college and my grades have also started to drop, need advice quick!
| Response from Dr. Conway
You came to the right place and definitely asked the question at the right time. I am writing this answer from Warsaw, Poland, as the European AIDS Conference winds up. There was a study presented by Drs. Ward and Kantor from Washington DC. They looked at 37 individuals who were on Sustiva-based therapies, had undetectable viral loads and had side effects such as yours. They changed the Sustiva to Viramune, by adding Viramune at 200 mg/day for two weeks, then increasing the Viramune to 400 mg/day and only then stopping the Sustiva. There was 1/37 that had liver problems that immediately improved when the treatment was changed to Trizivir. The other 36 did fine, and the side effects disappeared in 24/36 cases.
If you change to Viramune, there is now information to suggest that it is highly likely to help, and it won't affect your viral load.
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