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Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
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Triglycerides at 580 Follow-up
Oct 31, 2003

Dr. Conway, I appreciate your reply, but I have to admit, now, I am totally confused. My drugs are very effective, but ... the but says I might switch from Kaletra to nevirapine (Viramune)or efavirenz (Sustiva)or abacavir (Ziagen and you talk about atazanair (Reyataz) and boost with ritonivir (Norvir). Holy Cow, what should I do? Secondly, should I switch from Lopid to Tricor or should I consider an Aids Clinical Trial Group at Indiana University that would put me on something called Nyaspan? I know you doctors need to use the generic name of drugs, but I had to look all of those you used just to know which was which. Now that I've done a lot of research, I am still questioning what should I do. Please tell me as directly as you can. Thanks, JKJ

Response from Dr. Conway

The treatment of HIV is all about choices, and we are indeed fortunate to have many (good) choices available to us in most cases.

Here, the change in treatment for which there are the most data is to substitute nevirapine (Viramune) for the Kaletra, due to the fact that it might have the most beneficial effects on your lipids. You may wish to look into this first.

As far as any other treatment for your lipids, I am DEFINITELY in favor of clinical trials, since this is how we best learn what to do for the next guy. However, if you change to Viramune, you may not be eligible for the study, but that shouldn't influence your choice of changing to Viramune or not, if your priority is to lessen your pill load while still maintaining your viral load as low as possible.

Good Luck...

Started treatment this year, CT shows splenomegaly
Expected time until treatment failure, near perfect adherence

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