|sustiva/combivir side effects
Sep 5, 2003
I seroconverted a little over one month ago, and was started on Combivir and Sustiva right away. I am slowly adjusting to the medication, but one thing that has not let up is quite inconvenient. In the morning, about 20 minutes after I wake up, I have an extreme urge to defecate, and I go, but the urge does not go away -- in about 20 more minutes, it comes back, with some pretty extreme cramping. The feeling lasts for the first 4 hours of my day, which is not compatible with my daily schedule, and is causing some problems. I don't know if this is from the Sustiva, or Combivir, or something else, but it is pretty consistently every day. Is there something I can do about this? Will it go away? I can deal with feeling nauseous at work, as I have been, but this is quite bad. Please help. Thanks.
| Response from Dr. Henry
Could be the AZT part of the Combivir. You might consider trying to take the Sustiva in the AM to see if the pattern changes. I assume you have no other GI problems (H pylori, ulcers, proctitis, parasite infections, etc). An immodium before bedtime for a while might help the symptoms (oat bran, calcium supplements help some patients). If none of that helps then switching off one of your meds one at a time is often an approach that I consider. KH
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