Jun 11, 2003
Do you think everyone should get off the older protease inhibitors even if they are doing well and if not, why not?
Response from Dr. Henry
If patients are doing well on any of the older PIs (meaning their viral load is suppressed and they have few or no side effects) then there often is little reason to switch. I often switch patients to make a regimen simpler to take and to save the protease inhibitors for later use. Each patient has some unique issues germane to the decision. If a patient is doing well on their first PI regimen and is fully suppressed then the failure rate each year appears to be quite low (assuming the patient continue to be highly adherent). KH
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