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Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
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male breast enlargement
May 15, 2003

re: male breast enlargement I noticed a change in my breasts, particularly the right one, when i was on abacavir, ddi d4t. i stopped taking them for a few months, then started tenofovir,azt and kaletra. i am now taking tamoxifen for two months, with no decrease. what can i do?

Response from Dr. Henry

Use of some drugs (marijuana, female hormones, cimetidine, some antihypertensives, some antidepressants-etc), some medical conditions (such as obesity, liver disease, renal disease, testosterone deficiency, etc), familial conditions, and HIV associated liposytrophy are among the conditions associated with gynecomastia. Recovering from severe illness can result in gynecomastia also. Checking hormone levels (hCG, proloactin, testosterone, thyroid, etc) is often of some use. I am not convinced that tamoxifen helps that much. The course is variable and the linkage to particular HIV medications still under study. Plastic surgery or observation are also commonly used approaches depending on the situation. KH

drug strength affected by HIV meds?

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