Dec 18, 2002
Hi, thanks for your time in advance, Anyway my brother's CD4 count when he found out he was + in Feb 2002 was 117. At that time he had TB and PCP. He hospitalized for PCP and he got better. Started Combivir and Sustiva in April 2002. Took a lab test in Augest 2002 and his CD4 count went up to 485. The problem is he stopped the Medicine 2 months ago without telling to his doctor. The only side effect he had was darkening of skin and waight gain. Now yesterday he went to his doctor for check up and found out his cd4 count went down to 380. His doctor told him to start on DDI, D4T and Viracept. Is this the only option he has? What about if he start the old combo Combivir and Sustiva since it didn't give him much trouble? Please, please help us. Thank you so much for your time
Response from Dr. Henry
If he stopped the treatment when it was still working with no evidence for virologic failure then he probably could use the initial regimen again. I would not use D4T + ddI (too much toxicity=neuropathy, pancreatitis) for the NRTIs. There are likely numerous options available that a local HIV specialist could review with your brother. KH
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