Advertisement
The Body: The Complete HIV/AIDS Resource
Follow Us Follow Us on Facebook Follow Us on Twitter Download Our App
Professionals >> Visit The Body PROThe Body en Espanol
Read Now: Expert Opinions on HIV Cure Research
   
Ask the Experts About

Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
           
Rollover images to visit our other forums!
Recent AnswersAsk a Question
  
  • Email Email
  • Glossary Glossary


CYP 450 enzimes
Nov 14, 2002

Dear doctors Alprazolam (xanax) is a substrate of CYP 450 3A4. Sustiva that is inibitor/inductor of this liver enzimes should be create interaction like this psicotrope substance? And what is the difference from substrate-inducer-inibitor? Thanks Marcello

Response from Dr. Boyle

Although the effect of Sustiva on benzodiazepines is highly variable, Sustiva generally leads to increased levels of benzodiazepines, and these should be used with caution in patients taking Sustiva. Data have shown that lorazepam levels are not changed much by sustiva and no dose adjustment is required; however, 2 benzodiazepines (midazolam and triazolam) are not to be coadministered with Sustiva. I am not aware of any data that specifically addresses the use of alprazolam and you should discuss this issue with your doctor.



Previous
Abdominal Pain with Kaletra
Next
Nausea

  
  • Email Email
  • Glossary Glossary

 Get Email Notifications When This Forum Updates or Subscribe With RSS


 
Advertisement



Q&A TERMS OF USE

This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.

Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.

Review our complete terms of use and copyright notice.

Powered by ExpertViewpoint

Advertisement