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Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
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High Triglycerides
Oct 25, 2002

I just had my cholersterol rechecked which confirmed high triglycerides: Cholesterol 235, triglycerides 548, LDL 91, HDL 32. The triglycerides began rising after starting the meds.

I am currently on Retrovir, Sustiva, Ziagen with viral load non-detectable. I watch my diet and excercise regularly. I also take a multi-vitamin, garlic, vitamin E.

The high cholesterol worries me. My grandmother & father died of strokes.

My doctor wondered if I should start taking Lopid. Do you agree or should I try fenofibrate, niacin or fish oil? Should I change HIV meds? Any other recommendations? Thanks for your help.

Response from Dr. Henry

Exercise, diet and fish oil is a good place to start. If that doesn't help much then adding fenofibrate is usually the next step. The ACTG is soon to open a study using slow-release niacin for this situation (check for local availability of that study if interested). Switching off the Sustiva to ssome combination of lamivudine/tenofovir/nevirapine might also be an option on a trial basis depending on prior drug use and resistance situation. KH

Prophylactic Regimen with Combivir +Sideffects

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