Trizivir - Acid Reflux
Sep 25, 2002
My partner has been taking Trizivir for approximately 6 weeks. Almost immediately he began suffering HORRIBLE syemptoms from what the doc called GERD (Gastro-Esophogeal Reflux Disease). Attempts to mitigate this side-effect have included Prilosec with Zantac. He has also tried eating every 3 hours (which is damn near impossible cuz of all the crud in his stomach). No real success. I'm thinking the enteric coating on the Trizivir is the culprit, as he has had similar problems with Biaxin (which strangely enough has a very similar coating constituent). Are there different more effective meds to manage the GERD, or do we try seperating the Trizivir components out into their seperate forms. Seperated neither Abacavir, Epivir, or Zidovudine have enteric coatings. We're grasping at straws for a solution, as the Trizivir is working extremely well. Thank you for your time and kind consideration of our request.
Response from Dr. Henry
Has he been evaluated for H pylori disease and/or been seen by a GI specialist? Some patients simply have a hard time with AZT and less often abacavir. If there is no underlying GI disease that can be identified then perhaps switching meds around would be worthwhile. D4T, ddI, or tenofovir could be substituted for the AZT. KH
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