Aug 7, 2002
Hi. My name is Edgardo Bottaro, I work with HIV-infected patients (I am a physician) and one of them said me that another doctor prebscribed him buflomedil. She receives indinavir since 4 years ago. I think that buflomedil is an unuseful drug, but I need give her another answer about interactions between indinavir and buflomedil. i could not find nothing about the interaction, do you know something about it? Thank you.
Response from Dr. Henry
Buflomedil is not available to my knowledge in the US. It is a adrenergic agonists with some calcium channel blocker activity that is used for intermittent claudication and other indications. I don't know how it is metabolized since I could find nothing on it in US texts or perusing the web for pharmacokinetic studies. I would urge caution when combining with protease inhibitors in the absence of data evaluating any interaction. Sorry I could not be more helpful. KH
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