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Oxandrin's role in facial wasting
Jun 19, 2002

Can oxandrin cause or accelerate facial wasting? My doctor says no, but my face is telling me otherwise since starting therapy about six weeks ago. Your opinion will be appreciated.

Response from Dr. Henry

Use of oxandrin has not been identified as a risk factor for lipoatrophy in the setting of HIV treatment. It would not be expected to help that condition and I can imagine in some patients it might worsen it. If you are not wasting muscle but have a low testosterione level with weight loss/low energy then testosterone replacement might be preferred over oxandrin. Putting fat back on remains a challenge (exact cause still under study). Switching HIV meds around sometimes helps a bit but data is short term and improvement is modest at best early. KH



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