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Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
          
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combination therapies
Mar 14, 2002

My Dr. just put me on a combination therapy of combivir-viread-saquinavir. I just read on line that this combination is the worst drug combination drug therapy. This combination have, in several anecdotal reports, led to gastrointestinal distress, lymphomas, brain tumors, lung cancer, melanomas, WAC, candidiasis, Retinitis,PML, wasting syndrome, beer bellies, buffalo hump and many other AIDS related opportunistic infections and several deaths. This was published in 1998. Is this still true? Should I not take this combination? What combination should I take? Thank you for your help.

Todd Templin

Response from Dr. Henry

There are hundreds of possible combinations of 3/4 anti-HIV drugs. Each drug has its problems. The decision about which drug combination to use is complicated. The regimen you are on has not been extensively studied but is a reasonable one which actually may have les side effects than many others than could be chosen. In no way would I support the statement that your regimen is one of the worst--that simply is not true. What is best for you depends on lots of issues best understood by your HIV specialist (I do recommend getting care from a person who focuses on HIV care) who keeps up with this fast changing and complicated field. KH



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