Mar 11, 2002
My partner has had problems with his teeth and sciatica back pain due to a bad spine. He has heard that some medications can cause bone degeneration. Do you know anything about this?
Response from Dr. Henry
Corticosteroids are particularly linked to bone degeneration. Although the rate of osteporosis has been reported to be increased in the setting of HIV treatment, it is unclear what is the cause. More recent studies have not been able to link any one type of HIV drug to osteoporosis (thinning of the bones). Osteonecrosis of the hip has been linked particularly to use of corticosteriods. Dental problems and sciatica may be a separate issue--your partner needs to discuss with his HIV doc. KH
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