|PEP (Combivir) side-effects
Mar 8, 2002
I'm on my 4th day of a PEP regimen (lamivudine 150 mg and zidovudine 300 mg, twice a day, 28 days) after a potential exposure (unprotected anal insertive sex). The PEP was started roughly 44 hours after exposure. My question is, apart from the GI system side-effects I'm experiencing (mainly dyspepsia), I also have a sore throat, some coughing, and a blocked nose for part of the day. Could these ENT problems be Combivir-related? Or is this seroconversion occurring already!? I had had a sore throat, feverish feeling the day BEFORE the potential exposure -- could this cough etc simply be a "hangover" from that (and would the drugs exacerbate that)?
| Response from Dr. Henry
Those symptoms would be unusual to be due to the Combivir or HIV seroconcersion. Most likely those symptoms are an extension of your pre-existing cold like symptoms are some other upper airway cold or allergic reaction which are very common in the general population. KH
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