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Hair Loss & 3TC - Switch 1 of 3 Drugs? JB
Dec 5, 2000

I've been on Crix, AZT & 3TC since 1996 and have had an undetectable viral load and increasing CD 4 count to 550+. But in the last 6 months I been losing my hair. I would like to stop 3TC, but I don't know which drug I should substitute for the 3TC? Should I change them all? A little history -- I believe I was infected with a drug naive virus. Crix, AZT, and 3TC have been the only HIV drugs I've taken. I am tolerating the drugs. The only major side effect has been some neuropathy in my extremities up to now. I am also taking Diflucan, Clartin D, Propecia (Just Started), and Cardura 2mg for BPH.

Response from Dr. Bartlett

Hair loss can occur in persons with HIV infection, both on or off of antiretroviral therapy. Recently Crixivan has been linked with hair loss, and my guess is that it may be responsible for yours. I might start by switching your Crixivan to another drug.

John A. Bartlett, M.D.

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