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Lipodystrophy-Abdomen area
Jan 9, 2001

In the December/January issue of "hiv plus" there is an article stating studies conducted demonstrated that 1000mg of Niacin 3 times a day is successful in treating Lipodystrophy. Can you confirm this method for treatment of Lipodystrophy is effective? In addition, there is an advertisement in the January issue of "a&u" from Biomed Comm for their Homeopathic Preparation of the Growth Hormone. They state they are in compliance with FDA and FTC requirements. There claim is a reestablished youthful vitality, burn fat more efficiently, and increase lean body mass. If this is the case, would this be as effective a treatment as Serostim? Is there any new information regarding Lipodystrophy in the abdominal area and effective treatments.

Response from Dr. Boyle

Unfortunately, there is insufficient data to indicate that these are effective treatments for lipodystrophy. While Niacin may increase HDL, it has no effect on total cholesterol and there is no evidence that it will effectively decrease fat accumulations. In fact, most of the data I have seen indicates the contrary. There have been some studies that indicate that Human growth hormone (the real stuff), aerobic and resistance exercise, metformin and androgens have beneficial effects, but little else has made much difference. BB

Brian Boyle, M.D., J.D.

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