Dec 1, 2000
Dear Dr. Henry,
I started taking Zerit, Epivir, Vircept, Mepron and Diflucan (I just got over c. meningitis)and after 2 weeks my hair began to fall out, and a severe itchy rash developed. There is no history of baldness in my family and I eat balanced meals and take vitamins. My doctor is reluctant to change my meds since my CD4 count went from 4 to 136 in 2 weeks. Do you know of anything that might prevent further hair loss and in these cases is the loss total?
Response from Dr. Henry
In occasion patients one or more of the drugs you are on can cause hair loss (for example the most recent case in my practice was due to epivir -- ordinarily a very well tolerated drug with few side effects). If the rash is generalized that could be a sign of a drug reaction -- Diflucan can do that but that would be a key drug for your recent meningitis (but a switch to another oral anti-fungal might be considered if the rash continued=worsened). You might want to try and optimize your nutrition and hormone status (ie testosterone). Also, the first months on an effective HIV regimen can see all sorts of phenomenon occur due to the recovery of the immune system which then settles down. Many of my patients who have had hair problems like yours finally stabilize and improve later (either by riding it out or making a drug change). Your response to treatment is indeed impressive so any changes would need careful discussion with your HIV doc. KH
Keith Henry, M.D.
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