Please Note: Due to volume considerations, not all questions can be answered. Questions most likely to be answered will be those of general interest to a broad group of visitors to this forum. Questions pertaining to a specific case; requests for diagnosis, medical advice, or second opinion; or requests for opinions about untested alternative therapies will generally not be answered.
This Forum is made
possible in part by GlaxoSmithKline.
|
|
 |
|
My Cocktail has grown, again - side effects
May 1, 2008
I have been positive for nearly 3 years and went on meds about 8 months ago. I started on Truvada and kaletra but had troubles with diarrhea (incapacitating), so, my Doc changed the kaletra to norvir and prezista. Still the diarrhea but less trouble.
My numbers began to plateau and hover aroun 200 viral load, but my tcells came up to over 400. We recently added Isentress to see if we could break the plateau. Does this sound reasonable?
One of the biggest troubles I have started having is pretty severe (watery and frequent) diarrhea. It is sudden, frequent, and "explosive?". I have been on the Isentress for a little over 2 weeks now. Would this be the suspect?
Does anyone have any tips on how to mitigate the diarrhea? It is keeping me from venturing too far from home and effecting my work.
thank you!
B
|
 |
|
 |
|
Response from Dr. Henry
Boosted protease inhibitors using ritonavir cause annoying diarrhea in some paitients. Once daily dosing of Prezista using less ritonavir is beingt studied partly to see if that is better tolerated then the twice a day approach. A number of interventions help variably to diminish protease inhibitor related diarrhea including fiber tablets, calcium supplements, yogurt, or judicious drugs like Immodium or Lomotil. Looking for other causes (such as C difficule from earlier antibiotic use) need to be considered as well. KH
|
|
|
 Please remember that this forum is designed for educational purposes only, and experts are not engaged through this
forum in rendering legal or medical advice or professional services. Experts appearing on this page are independent and are solely responsible
for editing and fact-checking their material. Neither The Body nor any sponsor is the publisher or speaker of posted visitors' questions or the experts' material.
Questions and messages posted to this forum are not statements of advice, opinion, or information of The Body, Body Health Resources Corporation or any sponsor of this
forum. While neither The Body nor Body Health Resources Corporation regularly reviews posted content, we reserve the right to delete, move, or
edit postings if we deem it appropriate under the circumstances. Visitors submitting questions remain solely responsible for the content of their
messages.
Information provided by experts is general only and should not be used for diagnosing or treating a health problem or a disease, or relied upon as
legal or other professional advice. This information is not a substitute for professional advice or care. If you have or suspect you may have a
health or legal problem, you should consult your own health care provider or your attorney.
Copyright notice.
|
|
|
|
