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Ask the Experts about Managing Side Effects of HIV Treatment
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Kidney Stones
Jan 30, 2008

I just had a kidney stone detected. Is there any correlation to this and my HIV meds? I am taking Combivir and Sustiva for the last 4 years. My last CD4 count was 1197 and my VL has been undetectable for 3 years. I am also, taking Tricor, Zetia & metformin. Any ideas?

Response from Dr. Henry

I am not aware nor I have I observed a link between kidney stones and your current HIV regimen (stones are seen with some protease inhibitors such as indinavir and rarely atazanavir). Kidney stones are fairly common in the general popoulation and can have a range of risk factors (genetic, uric acid metabolism, calcium metablism and other issues) so often can occur independently of HIV infection/treatment. If any reader is aware of any published reports linked Combivir or Sustiva to kidney stones please post. KH



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