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Ask the Experts about Managing Side Effects of HIV Treatment
i was on sustiva/combivir and had slight muscle wasting. i switched to altripla about a year ago and have noticed recently that i'm gaining back muscle mass. is this possible, or am i nuts?
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Response from Dr. Henry
Muscle wasting has not been much of an issue for most patients taking Sustiva + Combivir whereas fat loss has been more of an issue. Switching from Combivir to Truvada has been shown to often reverse fat loss but not much observable effect on muscle mass. There could be a small percentage of patients who have muscle problems from the AZT in Combivir that would be stopped/reversed when switched to Truvada. KH
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