Advertisement
The Body: The Complete HIV/AIDS Resource
Follow Us Follow Us on Facebook Follow Us on Twitter Download Our App 
Professionals >> Visit The Body PROThe Body en Espanol
   
Ask the Experts About

Safe Sex and HIV PreventionSafe Sex and HIV Prevention
         
Rollover images to visit our other forums!
Recent AnswersAsk a Question
  
  • Email Email
  • Glossary Glossary


Not Taking PrEP Correctly?

Apr 16, 2017

A friend of mine did not follow guidelines before having unprotected sex. He took two tablets 30 hours before sex and then again 1 hour before having sex. what are the risk of catching HIv. What treatment should he follow. He has taken one more tablet 12 hours after.

Response from Mr. Jacobs

HI there - Your friend is fortunate to have you looking out for him. The approved regimen for taking PrEP varies a bit by geographical regions. In the United States, daily use is the recommended protocol by the CDC. (https://www.aids.gov/hiv-aids-basics/prevention/reduce-your-risk/pre-exposure-prophylaxis/).

However, in other parts of the world, the intermittent dosage strategy tested in the "Ipergay" trial is often recommended. This is a regimen that involves taking 2 doses of Truvada anywhere from 2 to 24 hours prior to any potential HIV exposure, than 1 dose 24 hours later, and another dose 48 hours later, and then daily if potential exposures are ongoing. (http://betablog.org/demand-prep-shows-high-efficacy-ipergay-trial/).

In the case of your friend, it sounds like he is loosely following the Ipergay protocol, but not exactly. It is quite possible that 2 tablets 30 hours before sex, and then one hour before sex may protect, but that wasn't measured in these trials. Also, taking only one dose following a potential exposure may provide protection, but whether or not it is sufficient enough wasn't studied.

I'd highly encourage your friend to sit down with his provider and figure out a proven workable plan to take PrEP that will maximize his protection. What he is doing now is not a proven strategy, and could result in acquiring HIV if exposed to a detectable viral load. If either you, or him, want to learn more about PrEP and dosing regimens, feel free to check out the international Facebook group page at "PrEP Facts: Rethinking HIV Prevention and Sex" (https://www.facebook.com/groups/PrEPFacts/).



Previous
Conceive Naturally with PreP?
Next
Unprotected sex with someone on Prep?

  
  • Email Email
  • Glossary Glossary

 Get Email Notifications When This Forum Updates or Subscribe With RSS


 
Advertisement



Q&A TERMS OF USE

This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.

Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.

Review our complete terms of use and copyright notice.

Powered by ExpertViewpoint

Advertisement